Department of Biological Chemistry, University of California, Los Angeles, 615 Charles E. Young Drive South, Los Angeles, California 90095, United States Department of Biological Chemistry, University ...

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Note that the information below summarizes the assessment of chlorinated alkanes and has not been updated. Chlorinated alkanes (formerly referred to as chlorinated paraffins) are substances found in a ...

The affinity maturation process of antibodies or B cell receptors (BCRs) constitutes a microevolution system for antibody improvement (1). During affinity maturation, multiple types of somatic ...

Aggregation of Cu–Zn superoxide dismutase (SOD1) is implicated in the motor neuron disease, amyotrophic lateral sclerosis (ALS). Although more than 140 disease mutations of SOD1 are available, their ...

In all analyzed structures of diverse P-loop NTPases, the conserved P-loop motif keeps the triphosphate chain of bound NTPs (or their analogs) in an extended, catalytically prone conformation, similar ...