Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...

While durable antibody responses from long-lived plasma cell (LLPC) populations are important for protection against pathogens, LLPC may be harmful if they produce antibodies against self-proteins or ...

Abdominal pain is considered chronic if it lasts for more than three months. The pain may be constant or it can come and go over the three-month period or longer. There are many health conditions, ...

E. cell and the L. E. phenomenon. There is still much to be learned about this disease, particularly the relation of chronic discoid lupus erythematosus to the acute disseminated form. With new ...

Chilblain lupus erythematosus (CHLE) is a rare type of cutaneous lupus erythematosus (CLE). Symptoms, such as lesions and swelling, can develop after exposure to cold temperatures. CHLE may have a ...

Petrolatum used as a control resulted in unchanged lesions. [123] A rheumatoid arthritis patient with recalcitrant chronic leg ulcers was reported to have almost complete resolution of lesions ...

I think we’re past the point where I have to explain that chronic pain is not the result of imbalanced humors or a wandering uterus or possession by demons. But for more modern skeptics ...

After learning that you have lupus, you might feel a sense of grief. It can take time to come to terms with being diagnosed with a lifelong chronic disease like lupus. Reflecting on the loss of the ...

In the Phase 2b CARE study, the investigational drug, cenerimod, demonstrated safe and effective results for treatment of adults with moderate-to-severe systemic lupus erythematosus (SLE). The drug’s ...

Objective Traditional initial treatment regimens for lupus nephritis (LN) used oral glucocorticoids (GC) in starting doses up to 1.0 mg/kg/day prednisone equivalent with or without a preceding ...

CLASHING APPROACHES TO CHRONIC DISEASE — Robert F. Kennedy Jr. — President-elect Donald Trump’s pick to lead HHS — wants to refocus health agencies on chronic disease. But House ...