Researchers investigate the sex-dependent microglial response to a colony-stimulating factor 1 receptor (CSF1R) inhibitor.

The study's findings are crucial in the rapidly emerging field of developing disease-modifying therapies that target microglia.

Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive.

Dr Caroline Sandford, climate scientist at the Met Office Hadley Centre. The rate at which atmospheric CO2 is increasing is now outpacing the pathways set out by the Intergovernmental Panel on Climate ...

We quantitatively compared seven OER pathways applicable to both the adsorbate evolution mechanism (AEM) and the lattice-oxygen-mediated mechanism (LOM) families, elucidating how iron significantly ...

Université de Bourgogne, U1231 INSERM, CTM, Equipe DesCarTes, UFR Sciences de Santé, 7 Bd Jeanne d’Arc, 21078 Dijon Cedex, France ...

Given the surge in nonbank lending, however, other pathways are opening up. "If you understand credit and you have some stomach for risk or are willing to do workouts to take control of companies ...

The individual contribution of each visual pathway when stimulating parts of the visual field remains unclear and is further obfuscated by the large spatial integration of EEG systems. We propose ...

“This evidence of how information flows between cells in choanoflagellate colonies demonstrates cell-cell signaling at the cusp of multicellularity,” stressed Colgren. The big takeaway is that a group ...

Previous studies have shown that IBDV infection antagonizes the type I interferon production to facilitate viral replication in the cell, and IRF7 signaling might play an important role. However, the ...

"The pathway impacts the hormone signalling that drives cancer, but it’s not susceptible to the usual mutations that drive drug resistance. Excitingly, we’ve shown that targeting this pathway ...