在新冠疫情这场全球性的风暴中，新冠病毒（SARS-CoV-2）的身影无处不在，它给人类健康和社会发展带来了沉重打击。SARS-CoV-2 主要侵袭呼吸系统，可很多患者在感染后，不仅呼吸出现问题，血液指标也变得异常，像是贫血、淋巴细胞减少和血小板减少等情况屡见不鲜。此前研究虽发现 SARS-CoV-2 ...

“Gene therapy for hemophilia A with the use of lentiviral vector-transduced autologous HSCs resulted in stable factor VIII expression, with factor VIII activity correlating to vector copy number in ...

Discover how hyperbaric oxygen therapy influences telomeres, stem cells, and mitochondria. New research reveals promising ...

Based on early Phase I/II data, investigators at Cincinnati Children's are enrolling more patients with a telomere biology ...

Early results from the company’s single-arm trial saw the therapy able to partially repair the chemical responsible for ...

present an important study that applied a high-resolution transposon-based barcoding system to show the clonal contribution of hematopoietic stem and ...

The Food and Drug Administration (FDA) has granted Orphan Drug designation to EXG-34217 for the treatment of telomere biology disorders.

Data published in NEJM Evidence detail the first clinical test of ZSCAN4 for telomere elongation.Treatment with EXG-34217 resulted in in vivo ...

Alveolar bone resorption (ABR) is a key pathological manifestation in the development of apical periodontitis (AP) that contributes to the AP-associated tooth loss, and whose underlying mechanism ...

Donor selection in T-cell-replete haploidentical donor peripheral blood stem cell transplantation. Leukemia. 2025;1-11.

为探究高原动物心脏适应机制，研究人员开展牦牛心脏中 Telocytes（TCs）的研究。结果发现其在主动脉球和心肌的分布、特征等。该研究为揭示高原动物适应环境的奥秘提供关键线索，值得科研读者一读。

The FDA recently granted EXG-34217 Rare Pediatric Disease Designation (RPDD) and Regenerative Medicine Advanced Therapy (RMAT) Designation.