为解决 NACT 对乳腺癌患者外周单核细胞影响及预后贡献不明的问题，亚历山大大学研究人员开展相关研究。结果发现 NACT 影响 CD14+CD16 + 单核细胞和 sCD163 水平，且二者与临床反应有关。该研究为乳腺癌治疗提供新思路，值得一读。

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Atherosclerosis cardiovascular disease (ASCVD)-related mortality is higher in patients with lupus nephritis (LN) compared ...

Methods Here, we characterised a kindred of two monozygotic twin girls with juvenile idiopathic arthritis at the genetic and immunological level, using whole exome sequencing, single cell sequencing ...

ucl.ac.uk Results Dysregulated mitochondrial-associated gene expression correlated with increased ISG expression in JDM CD14+ monocytes. Altered mitochondrial-associated gene expression was paralleled ...

Design Flow cytometry, immunohistochemistry, confocal imaging and gene expression analyses determined the phenotype, functional/transcriptomic profile and tissue topography of MerTK+ ...

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

Flow cytometry showed a total loss of CD16 in the granulocytes and loss of CD14 in the mature monocytes. Cytogenetic analysis on the marrow aspirate revealed a normal female karyotype (46,XX).

Xiamen Cell Therapy Research Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China ...

Gints Zilbalodis’ Flow, the animated film that had its world premiere at the Cannes Film Festival, has earned Latvia its first Academy Award nominations. The film landed Best Animated Feature ...

The contenders for the 97th Academy Awards ceremony have been unveiled, kicking off the final leg of the race for the international honor. By Georg Szalai Global Business Editor ...