All lymph node biopsy samples were stained for CD19 (pan B-cell marker), CD20 (pan B-cell marker), CD138 (plasma cells), CD23 (follicular dendritic cells (FDCs)), PD-1 (follicular T helper cells, TFH) ...

Multi-laser picodroplets can be used in single cell analysis, sorting and dispensing - discover how in this article.

B Confocal images of GalT-GFP-SNAP (green) and TMR-Star (red) in HeLa cells stably expressing the Golgi-resident GFP-fused SNAP-tag construct (HeLa GalT-GFP-SNAP). Actin (phalloidin, white) and nuclei ...

The pre-B-cell receptor (pre-BCR), which comprises two Igμ chains and two germline-encoded surrogate light chains (SLC) that are associated with the signalling subunits Igα and Igβ, is formed ...

The ability to efficiently isolate antigen-specific B cells in high throughput will greatly accelerate the discovery of therapeutic monoclonal antibodies (mAbs) and catalyze rational vaccine ...

CMRI researchers discovered that DNA repair pathways control how cancer cells die after radiotherapy. Blocking a key repair ...

B cells are involved in autoimmune diseases through both antibody-dependent and -independent mechanisms. Broad depletion of B cells using monoclonal antibodies (mAbs) such as anti-CD20 or CD19 were ...

Intravascular large B-cell lymphoma (IVLBCL) is a rare type of non-Hodgkin’s lymphoma. Its symptoms can vary, making it difficult to diagnose. The outlook for people with IVLBCL is typically poor.

Dr G G Forstner, Division of Gastroenterology and Nutrition, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada email:gforst{at}sickkids.on.ca BACKGROUND AND AIMS ...

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells ...