Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments ...

These chains are interconnected by disulfide bonds, resulting in a characteristic Y-shaped structure with a total molecular weight of approximately 150 kDa. Each antibody molecule possesses ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

Optimized constant domains enable the rapid generation and idenitification of development candidates that retain critical structure-function characteristics (Fig. 1). Antibodies from AlivaMab ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell.

Although the history of ADC development spans decades, recent clinical successes — along with advances in antibody engineering, chemical synthesis and cancer biology — have brought a ...

From left, Florida State University faculty researcher Fanny C. Liu and Christian Bleiholder, a professor in the Department ...

Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could ...

An antibody is a component of humoral immunity ... with level 4 designated for use with the most hazardous agents. Deoxyribonucleic acid, the chemical structure that contains the genetic information ...

Fellow UT researchers, who were the first to decode the structure ... and molecular biology in UT's College of Natural ...