In Alzheimer's disease (AD), amyloid β-protein (Aβ ... proteins were unusually rich in highly ordered, β-pleated sheet structure, providing an apparent explanation for their long-known property ...

An illustration depicts cells in an Alzheimer’s-affected brain, with abnormal levels of beta amyloid protein clumping together to form plaques that collect between neurons and disrupt cell function.

The protein amyloid beta, which occurs naturally in the brain ... They then used 3D light-sheet microscopy to study plaque formation throughout the brain, providing a complete picture of amyloid ...