Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Sir Keir Starmer has claimed the Conservatives are the “coalition of blockers” as he defended ... business costs from £600 million to £1 billion-a-year in sick pay. That will mean higher ...

Busà Photography / Getty Images Many people believe that being wealthy means having a nice house, a late-model car, and a summer cottage, but the kind of money possessed by the wealthiest 1% of ...

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Typically, puberty blockers alone do not cause permanent changes ... presenting with signs of precocious puberty as young as 1 year old who then use this medication for 7 or more years, explains ...

24, 2025 (HealthDay News) -- There is considerable uncertainty regarding the effects of puberty blockers in young individuals ... Abstract/Full Text 1 (subscription or payment may be required ...

In an NIH-sponsored trial, researchers examined whether an α-adrenergic-receptor blocker — a drug commonly ... 6 weeks (median symptom duration, 1.2 years) and scores ≥12 on a 43-point ...

These compounds exhibit selective binding to tumor necrosis factor receptor 1 (TNFR1) and hold the potential for mitigating the progression ... while TNFR2 facilitates immune modulation and tissue ...

The first direct and selective interleukin-1 (IL-1) receptor antagonist, anakinra can be used alone or in combination with any of the other DMARDs, except those in the tumor necrosis factor (TNF ...

The other has to do with reducing inflammation. He said there’s also appears to be an effect in the brain, which has GLP-1 receptors, and in the lining of the blood vessels. Some of the most ...

Fortunately, large scale randomised trials with GLP-1RA-based therapies that yield greater weight loss are ongoing and several will report out in the next 1-4 years. Such trials will lead us much ...

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...