Design Human HCC cell lines and HCC mouse models were used to assess the therapeutic efficacy and targeted molecular pathways of cabozantinib, either alone or in combination with the pan-mTOR ...

No one wishes for their meticulously crafted look to be spoiled by surplus oil. Consequently, oil blotting sheets can be a game-changer. Created to soak up additional skin oil, these convenient ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. mTOR plays a pivotal role in cancer growth ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The problem of microplastics (MPs) pollution has caused many health risks to residents ...

On a recent winter afternoon in downtown Truckee, the sun dipped behind the mountains as a full moon rose above Donner Pass Road, the California city’s main thoroughfare. As the temperature ...

we found that ADM2 facilitates the expression of insulin-like growth factor 2 (IGF-II), which then triggers the activation of the AKT-GSK3β-mTOR signaling pathway via the IGF-II receptor (IGF-IIR ...

The Western genre is one of the oldest and cherished film genres to ever enter the landscape of cinema and successfully transitioned into the Talkies, only growing immensely popular among movie goers.

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“What you got ain’t nothin’ new,” drawls Ellis (Barry Corbin) to Sheriff Bell (Tommy Lee Jones) in the Coen brothers’ Oscar-winning neo-Western film “No Country for Old Men.