This is a neat and “elegant system to induce epigenetic aging, that is, to create DSBs in cells and mice without causing mutations,” writes Chinese Academy of Sciences aging researcher Guang-Hui Liu ...

Dubal said, referring to the silent X chromosomes. The study was done in aging mice, but the researchers believe the finding is applicable to humans because mice show the same age-related effects ...

In their latest study, published in Nature Aging on March 7, first author Lorna Jayne, Hrvatin, and colleagues show that inducing a prolonged torpor-like state in mice slows down epigenetic changes ...

Details of this study done in mice have been published in a Science Advances paper titled, “Aging activates escape of the silent X chromosome in the female mouse hippocampus.” In it ...

By the 9-month mark, the torpor-like state had reduced blood epigenetic aging in these mice by approximately 37%, making them biologically three months younger than their control counterparts.

The experiment involved mice born to live fast and die young, bred with a rodent version of progeria, a condition that causes ...

They explored whether blocking this receptor could reduce the harmful effects of aging in the eye. To achieve this, researchers treated aged mice with montelukast (MTK), a drug commonly used for ...

"By targeting a network of vessels outside of the brain that is critical for brain health, we see cognitive improvements in mice, opening ... benefits for a naturally aging brain." ...