CBL-514, the world's first investigational drug for large-area localized fat reduction, has demonstrated significant efficacy in its second and the last Phase 2b ...

CBL-514, the world's first investigational drug for large-area localized fat reduction, has demonstrated significant efficacy in its second and the last Phase 2b study (CBL-0205) before Phase 3.54.2% ...

For the in vitro study, the authors used conditioned mediums derived from different tumor cell lines to induce C2C12 myotube atrophy and 3T3-L1 adipocyte lipolysis; C26 and LLC tumor-bearing mouse ...

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo. Oral administration of Z526 slowed ...

The study was published Jan. 28 in the Journal of Investigative Dermatology. Previous research has shown that during fibrosis, fat cells in the skin called adipocytes are depleted. Why that happens ...

One of the manifestations of adiposopathy is a relative increase of intra-adipocyte lipolysis over that of intra-adipocyte lipogenesis, leading to a net release of FFAs, insulin resistance and ...

A recent case report by Sahota and colleagues has provided new insights into treatment of dysglycemia via dopamine (DA) receptor stimulation in the setting of autoimmune diabetes (1). Briefly, a ...

Postpartum insulin supplementation significantly reduces the change of adipocyte size in obese cows, which is beneficial to buffer the intense lipolysis and adipose tissue remodeling caused by more ...

Dr Maeda is an expert in adipocyte and cardiovascular biology. Tohru Funahashi, Tohru Funahashi is Associate Professor of Metabolic Medicine in the Graduate School of Medicine, Osaka University ...