Primary human brain microvascular ECs (HBMVECs; Applied Cell Biology Research Institute, Kirkland, WA, USA) and immortalized primary HBMVECs (hCMEC/D3) were used in experiments with consistent and ...

Segregating the outer and inner meningeal compartments is the epithelial-like arachnoid barrier cells, connected by tight and adherens junctions, which regulate the movement of pathogens, molecules, ...

"Our work also shows the importance of force transmission to be regulated by the ability of epithelial tissues to interact with each other through adherens junctions with potential in ...

TNF, tumor necrosis factor; AJ, adherens junctions; TJ, tight junctions; GJ, gap junctions; MLCK, myosin light chain kinase; PAMP, pathogen-associated molecular pattern; DAMP, damage-associated ...

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In normal cells, Kbu marks were linked to adherens junctions and ion transport. In contrast, in CRC cells, they were associated with mesenchymal proliferation and apoptotic signaling, reflecting ...

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Correspondence to Professor Jun Yu, Institute of Digestive Disease, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; ...

Protein interactions play a crucial role in regulating cellular mechanisms, highlighting the need for effective methods to control these processes. In this regard, chemical inducers of proximity (CIPs ...

Your doctors consider many factors to help them decide about your treatment. These include: how far your cancer has grown or spread (the stage) your general health and level of fitness the type of ...

Peter Grünberg Institut (PGI-9), Forschungszentrum Jülich, 52425 Jülich, Germany ...