The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

DelveInsight’s, “HDAC Inhibitor Pipeline Insight” report provides comprehensive insights about 40+ companies and 50+ pipeline ...

and treatment of rheumatoid arthritis with osteoporosis (OP) in the future. Efforts will be made to reach an academic consensus as soon as possible to fully utilize the unique advantages of TCM in ...

This review summarizes the research progress of CP in the medical field in the past 5 years. By searching and analyzing the literature, and combining with Cytoscape software, we comprehensively ...

Shares in the UK's IP Group slid today after it revealed that an arthritis drug in development at one of its portfolio ...

Rheumatoid arthritis (RA ... in the etiology of anti-CCP-positive (but not anti-CCP-negative) RA A possible mechanism behind the interaction between smoking, HLA-DR shared epitope genes and ...

In phase II and III clinical trials of active rheumatoid arthritis, leflunomide was shown to improve primary and secondary ... the interruption of de novo pyrimidine synthesis may be the primary mode ...

PORTLAND, KS, UNITED STATES, February 13, 2025 /EINPresswire / -- Rheumatoid arthritis is an autoimmune disorder, w ...

By addressing this key driver of inflammation, CIT-013 has the potential to offer a differentiated and comprehensive treatment option for conditions such as rheumatoid arthritis and hidradenitis ...

Objectives Tendinopathy is a frequent clinical problem and represents an extraordinary health economic and socioeconomic burden with high unmet medical needs. Recent clinical evidence suggests ...

IP Group said on Monday that its portfolio company Istesso has reported results from a phase 2b study of its investigational ...

Their analysis also led to the discovery of previously unknown mechanisms for known medications ... However, investigating such modes of action for a whole compound library would have been ...