Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

That is, transcriptional activation was associated with methylation at K4, which paralleled acetylation of K9 and K14, while transcriptionally inactive chromatin was associated with K9 methylation.

More information: David Dansu et al, Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors, Journal of Cell Biology (2024). DOI: 10.1083/jcb.202308064 ...