The discovery of a new bat coronavirus in China has sparked concerns of another pandemic. The virus, HKU5-CoV-2, is similar ...

Researchers have tested the efficacy of the angiotensin-converting-enzyme (ACE) inhibitor perindopril at reducing aortic stiffening and dilatation—two of the most serious complications of MFS ...

What was needed was a simple quantitative assay for this enzyme. With this in mind, I developed a spectrophotometric assay to purify rabbit lung ACE (ref. 5) and to study its enzymatic properties ...

A Chinese team discovered a new bat coronavirus that poses a risk of animal-to-human transmission as it uses the same human ...

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers are commonly used to treat hypertension and/or a range of progressive end-organ diseases. The success of each of these ...

The virus is able to bind to the human angiotensin converting enzyme, the same receptor used by the Sars-CoV-2 virus, which ...

Hypotension is not a specific side effect with ACE inhibitors; rather, it is a broadening of the physiologic action of these drugs that occurs most commonly when a patient becomes volume contracted.

Off-label uses outside of the drug's formal Food and Drug Administration (FDA) approval can include migraines and other ...

A media report underscores that the virus, found by a Chinese team of virologists, uses the same human receptor as the virus ...

Angiotensin converting enzyme inhibitors are a class of oral medications that act primarily through blockade of the angiotensin converting enzyme. This enzyme converts angiotensin I to angiotensin II.