Advanced maternal age (AMA) placenta exhibited premature aging, presumably resulting in trophoblast dysfunction, inadequate placentation. However, the precise reasons and mechanisms of trophoblast ...
The role of EVTs play in the completion of arterial remodeling is also highly dependent on the ability of migration/invasion into the decidual stroma. Inadequate trophoblast migration and invasion or ...
The outer membrane (chorion) and trophoblast layer of the placenta are derived from the trophoectoderm of the blastocyst cells. Other extra-embryonic tissues, including the amnion (inner membrane ...
Marking the second global approval after Japan, the U.S. FDA has approved Datroway (datopotamab deruxtecan), a trophoblast cell surface antigen 2-directed antibody-drug conjugate (ADC) from Daiichi ...
It combines a monoclonal antibody, datopotamab, that targets trophoblast cell surface antigen 2 (TROP2), a protein commonly found in high levels on breast cancer cells, with the chemotherapy drug ...
Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...
1 Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK 2 Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK Correspondence to Clare Teresa ...