Université Clermont Auvergne, Clermont Auvergne INP, CNRS, ICCF, 63000 Clermont-Ferrand, France ...

华盛顿州立大学成功开发出具有人类样端粒的人源化TERT小鼠模型，即“HuTa”小鼠，这一成果为衰老疾病和长寿的研究开辟了新途径，有助于提高健康生活质量，对抗年龄相关疾病提供了宝贵资源。研究人员将利用该模型开展多方面研究，包括端粒缩短、癌症和压力对衰老 ...

The recently updated, open-access FCCmigex database now compiles information on 5,294 food contact chemicals from packaging and other food contact articles across 1,500 scientific studies. Latest ...

The criticisms expressed by the European Commission regarding Hungarian public procurement cannot be substantiated ...

Methanolysis of polyethylene terephthalate to dimethyl terephthalate is a sustainable route for recycling of polyethylene ...

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against ...

The escalating global plastics crisis, exemplified by the >31 million tons of PET production in 2019, necessitates efficient recycling strategies as ...

研究结论和讨论部分指出，IVDD 由多种因素引发，当前治疗手段无法阻止其进展。本研究首次证实 Piezo1 参与 IVDD，它通过增加软骨细胞 ROS 生成、提高氧化应激水平、促进 ECM 降解、引发炎症反应和诱导细胞凋亡等方式，推动椎间盘退变。Yap 在 Piezo1 下游发挥作用，介导其信号转导。抑制 Yap 可改善 CEP 退变。这一研究为 IVDD ...

The best gas pressure washer can have you deep-cleaning the patio, deck, siding, and other surfaces easily. Explore the top ...