运输条件：美国大陆的室温；其他地方可能有所不同。 产品活性：Streptozotocin (Streptozocin; STZ) 是一种广泛用于实验动物诱导糖尿病模型的抗生素。Streptozotocin 通过葡萄糖转运体 (GLUT2) 进入 B 细胞并引起 DNA 的烷基化 (DNA-methylating)。Streptozotocin 可诱导 β 细胞凋亡。

The erratic lifestyle routine and irregular eating habits often results in lifestyle diseases and health issues that lead to ...

为解决虾青素口服生物利用度低问题，研究人员将其制成纳米乳用于 AD 大鼠研究，发现能改善认知功能。 天然来源的虾青素具有出色的抗氧化和抗炎作用，目前作为一种神经保护剂被广泛研究。然而，虾青素的口服生物利用度较低。因此，研究人员将雨生红球藻（Haematococcus pluvialis）提取的虾青素制成纳米乳，以提高其生物利用度，并给予类似阿尔茨海默病（Alzheimer’s disease，AD ...

研究结论和讨论部分指出，该研究首次证明 1 型糖尿病会 “揭开” 阿霉素治疗引起的亚临床心脏毒性。其机制主要涉及心肌细胞死亡增加，进而导致细胞外基质重塑，最终引发心脏收缩功能障碍和死亡。这一研究结果对癌症幸存者意义重大，因为他们患心血管疾病（如糖尿病）的风险较高，而糖尿病可能会 “唤醒” 化疗药物隐藏的心脏毒性。虽然研究存在一定局限性，如仅模拟了 1 ...

Myocardial remodeling is a key pathophysiological basis of heart failure, which seriously threatens human health and causes a severe economic burden worldwide. During chronic stress, the heart ...

Heart failure is a pathological condition in which the heart is unable to pump enough blood to the rest of the body, because it is either unable to fill with a sufficient volume of blood or unable ...

Biological models are experimental systems that recreate aspects of human tissue function or disease. For example, certain tumour cell lines may serve as cancer models, and transgenic mice that ...

The nuclear factor of activated T cells (NFAT5), also known as a tonicity-responsive enhancer-binding protein, was originally identified as a key transcription factor involved in maintaining cellular ...

Nutritional yeast is a dairy-free and usually gluten-free way to add a savory, nutty flavor to dishes. It provides vitamins, minerals, and protein to the diet. Benefits may include boosting energy ...

Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, South Australia, Australia (K.R.P., J.T.M.T., V.A.N., L.G.S., E.L.S., P.J.P ...