A 5.5 Å electron density map of ribonuclease has been obtained by X-ray diffraction using five isomorphous derivatives. One of the cystine residues is identified by means of a chemically modified ...
【导读】 利用核糖核酸酶靶向嵌合体(RiboTACs)降解RNA,是一种很有前景的癌症治疗方法。然而,潜在的脱靶降解是一个严重的问题。在这项研究中,团队设计了一种能触发肿瘤微环境激活的RiboTAC。
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
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News Medical on MSNDysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritisAnnouncing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published ...
Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...
Importantly, ManS was produced by a noncanonical biogenesis mechanism: The ribonuclease RNase III, which usually cuts double-stranded RNA, cleaves at a single-stranded region in the mRNA 3'UTR.
The metastasis of malignant tumors determines patient prognosis. This is the main reason for the poor prognosis of patients with cancer and the most challenging aspect of treating malignant tumors.
Fruits, roots, stems, leaves, and flowers of Satsuma mandarin (Citrus unshiu Marcov. Variety Miyagawa wase) were obtained from Linhai, Zhejiang province, China. Uniform fruits were harvested at five ...
At least 250 million people worldwide are chronically infected with HBV, a small hepatotropic DNA virus that replicates through reverse transcription. Chronic infection greatly increases the risk for ...
Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, ...
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