Several studies have shown how α-synuclein, amyloid-β, tau and other amyloidogenic proteins can act as nucleating particles and thereby share properties with misfolded forms, or strains, of the prion ...

They now run a lab at the Broad Institute in Boston. By 2024 they had created an editor that, in mice, turns off the prion ...

The new gene therapy aims to address the root cause of prion disease by using the CHARM epigenetic editing platform from the Whitehead Institute to target and silence the gene that codes for the ...

Prion Protein (PrP) is a normal protein found in healthy cells, though its exact role is not yet clear. However, when this protein changes shape into a misfolded form, it becomes infectious and is ...

School of Chemistry, Indian Institute of Science Education and Research Thiruvananthapuram (IISER TVM), Vithura, Thiruvananthapuram 695551, India ...

For decades, chronic wasting disease has plagued Colorado’s deer, elk and moose herds. While Colorado Parks and Wildlife has ...

Episode 151For the Love of Goats As goat owners, understanding diseases that can affect our herds is crucial for maintaining ...

The protein solutions that we investigate with our coarse-grained simulations must be ... A Data-Driven Scaling Law Approach for Studying Phase Behavior of Prion-like Domains Scaling laws can reveal ...

Protein helps to build and repair muscles, which is especially important if you’re focused on fitness and working out. These are the top protein powders tested by our experts. A quick stroll ...

Bob Schuh's 'Scoping the Great Outdoors' has news from Manitowoc County Lakes Association, Maribel Sportsman's Club and the ...

Immunoblotting was performed with ab3531 (Abcam). Formalin-fixed brain halves divided at the midline (left hemisphere) were treated in formic acid (95%) to deactivate prion infectivity before being ...

This study reveals that prion protein (PrP) promotes copper toxicity in Wilson disease by facilitating copper endocytosis. The authors demonstrate that suppressing PrP reduces copper overload and ...