A new integrated 3D imaging approach combines cryo-light microscopy and soft X-ray tomography to reveal the intricate ultrastructure of herpes simplex virus-1 assembly.

A new combination of microscopy methods has revealed exquisite detail of the virus assembly process used by herpes simplex ...

Specifically, after primary envelopment, capsids undergo nuclear membrane fusion and de-envelopment, and then the nucleocapsids bud from the nucleus and are transported to the TGN, where the tegument ...

First, VP16 is a transcriptional activator that regulates viral gene transcription. Second, VP16 is a late tegument protein that further participates in the assembly and maturation of nucleocapsids in ...