SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in ...

In a study published online March 10 in Cancer, authors identified gliomas with mutational signatures associated with ...

Add a description, image, and links to the deep-mutational-scanning topic page so that developers can more easily learn about it.

Using glioma tumor samples, researchers looked for genetic mutational signatures, finding one previously associated with ...

Gleevec response in GIST varies by mutational profile, with KIT-exon-11 mutation linked to better outcomes, emphasizing ...

A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. Purpose: Understanding the mutational landscape ...

Firefighters might face a higher risk of brain cancers caused by exposure to chemicals in fire extinguishers, a new ...