Nature4mon
The evolution of our thinking about microRNAs
The 5′ seed model has been successful in identifying potential targets of microRNA families, but we need a better understanding of the roles of nucleotides outside the seed for parsing the roles ...
EurekAlert!1mon
Polymorphism in the Hsa-miR-4274 seed region influences the expression of PEX5 and enhances radiotherapy resistance in colorectal cancer
The research identified a significant association between a single-nucleotide polymorphism (SNP), rs1553867776, in the seed region of miR-4274 and CRC radiosensitivity. PEX5 was revealed as a ...
Healio14d
‘Striking’ finding: MicroRNA may predict COVID-19 mortality risk among people with cancer
Researchers have identified two microRNA that may predict which individuals with cancer are at elevated risk for COVID-19-related death.Low levels of hsa-miR-150-5p and hsa-miR-93-5p in COVID-19 ...