Loss of TSC gene function leads to dysregulated mechanistic target of rapamycin (mTOR) signalling. As mTOR is a regulator of lipid and nucleotide synthesis, we hypothesised that the serum metabolome ...

Mammalian target of rapamycin (mTOR), an evolutionarily conserved serine/threonine protein kinase, serves as a central regulator of cell growth, proliferation, and survival by coordinating nutrients, ...

The hallmarks of cancer include dysregulated metabolism and immune evasion. As a basic way of metabolism, lipid metabolism is reprogrammed for the rapid energy and nutrient supply in the occurrence ...

She has spent most of her career counseling patients with diabetes, across all ages. Cholesterol is a waxy substance made by your liver and found in foods like meat, dairy, and tropical oils.

His team identified PanK4 as a key regulator of energy metabolism in skeletal muscle, regulating glucose uptake and fatty acid oxidation and being activated by physical exercise. The study suggests ...

Following a healthy diet, exercising, and not smoking are the most commonly recommended natural ways to manage cholesterol. Natural supplements like berberine, flaxseed, omega-3 fatty acids ...

Brian T. Feeley, MD, FAAOS, was bestowed with the 2025 Kappa Delta Elizabeth Winston Lanier Award for his research in ...

Light to moderate alcohol drinking can raise HDL, but heavy drinking can increase total cholesterol, LDL, and triglycerides. This raises the chance of developing cardiovascular disease.

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Physical activity is not only important for fitness but also for overall health. This is confirmed by a new study, which identified PanK4 as a key regulator of energy metabolism in skeletal muscle, ...