Get Instant Summarized Text (Gist) A mechanism regulating mRNA poly(A) tail length in early embryos has been identified, involving the protein MARTRE1, which inhibits the CCR4-NOT complex. MARTRE1 ...

During the oocyte-to-embryo transition (OET), the length of the mRNA poly(A) tail is closely linked to its translational efficiency. Regulation of the poly(A) tail is essential for selective ...

This approach might shift our view of biological processes that once seemed locked into a narrow ideal. Researchers have spent decades mapping the genetic signals that guide a Drosophila embryo, which ...

Localization of MRP4 was tested with immunohistochemistry. Results Expression levels of MDR1, URAT1, OAT1, OAT3, and OCT2 increased with age, but levels of MATE1 and GLUT2 were stable from birth.

PGC-1α regulates transcription of the gene encoding mitochondrial transcription factor A (TFAM), and immunofluorescence analysis indicated significantly lower TFAM expression in the 16-cell KD embryos ...

Expert Rev Vaccines. 2012;11(1):55-67. A summary of the events taking place after intradermal injection of naked mRNA is given inFigure 1. Although formulation of mRNA vaccines and sophisticated ...

Their mathematical model forecasts the ideal body plan of a fruit fly's early embryo, suggesting that ... The fruit fly Drosophila, as biologists refer to it, is a widely studied organism ...

The responses of m 6 A methyltransferases and reader protein under the condition of genomic imbalance.

This study convincingly shows that aquaporins play a key role in blood vessel formation during zebrafish development. In particular, the paper implicates hydrostatic pressure and water flow as ...

The mRNA vaccine against avian influenza presents several advantages and disadvantages: Advantages: Rapid Development and Production; Non-Infectious Nature; Strong Immune Response; Adaptability to ...