The development of a modular, phage-based expression system optimized for Pseudomonas putida enables stringent, tunable and high yield expressions with minimal cytotoxicity. During urinary tract ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

Integration of RT-encoding bacteriophages into host genomes through lysogenic infection is common. This study identified numerous prophages encoding RTs in the complete or nearly complete genomes ...

细菌对抗生素的耐药性给社会带来沉重经济和健康负担，探索针对多重耐药菌的新方法迫在眉睫。噬菌体作为细菌的天然捕食者，噬菌体疗法一直被视为治疗耐药菌感染的潜在手段，在尿路感染治疗方面也备受关注。然而，临床实验中噬菌体抗菌治疗 UTI 的效果并不持久。

melitensis strains. The Y17 genome spans 38,025 bp with a GC content of 48.2%, making it the smallest genome among brucellaphages to date. It lacks virulence, antibiotic resistance, or lysogenic genes ...

Advances in synthetic biology and the clinical application of bacteriotherapy enable the use of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small ‘machine factory’ ...

Central European Institute of Technology, Masaryk University, Brno60200, Czech Republic National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno60200, Czech Republic ...

This repository contains all scripts and data tables used for the analysis of viruses in total metagenomes generated from upland peatland soils in the UK, as presented in Kosmopoulos et al. (2025; in ...