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生物通
23 小时
细胞衰老程度可预测良性乳腺疾病患者的乳腺癌风险
研究结论表明,基于深度学习模型预测的乳腺上皮和脂肪组织中的核衰老评分,能够有效预测 BBD 女性患乳腺癌的风险。多个预测模型结合空间分布模式分析,更能揭示出与乳腺癌发展相关的生物学机制。这一发现为改善数百万 BBD 患者的癌症风险评估提供了新的方法,仅需利用活检时已获取的 H&E 染色切片即可进行评估。
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