Growing up, Dr. Melody Campbell, 38, was part of the Campbell Quartet. Little did she know, she’d embark on a career to lead ...

Researchers at Vaxart Inc. and the Center for Vaccine Development at the University of Maryland School of Medicine evaluated ...

Discontinuation of BEACON-IPF following DSMB and outside expert panel recommendationSOUTH SAN FRANCISCO, Calif., March 03, 2025 (GLOBE ...

Pliant Therapeutics, Inc. (Nasdaq: PLRX) today announced that following a prespecified data review and recommendation by the trial’s independent Data Safety Monitoring Board (DSMB), as well as a ...

While the exterior of vertebrate bodies appears bilaterally symmetrical, internal organ positioning and morphology frequently exhibit left-right (L-R) asymmetries. In several vertebrates, including ...

Credit: Nano Letters (2025). DOI: 10.1021/acs.nanolett.4c05858 When ultrasound was applied to cancer cells grown on the 50 nm and 70 nm platforms, their cell membranes were found to stretch due to ...

Pliant Therapeutics, Inc. (Nasdaq: PLRX) today announced that following a prespecified data review and recommendation by the trial's independent ...

Integrins are transmembrane glycoproteins that mediate attachment of cells to the extracellular matrix or to other cells via interactions with proteins such as fibronectin and collagen.

Acute skin wound healing is a multistage process consisting of a plethora of tightly regulated signaling events in specialized cells. The Thy-1 (CD90) glycoprotein interacts with integrins and the ...

Table 1. Major mammalian phagocytic integrins and their invertebrate orthologues. Integrins are characterized by requiring activation to be functional. This review has focused on the main events ...

Integrins require an activation step prior to ligand binding and signaling. How talin and kindlin contribute to these events in non-hematopoietic cells is poorly understood. Here we report that ...