BMJ4 天
Infrapatellar fat pad of patients with end-stage osteoarthritis inhibits catabolic ...
Explants of bovine cartilage were cultured with or without FCM. Nitric oxide (NO) and glycosaminoglycan release and gene expression of matrix-degrading enzymes in cartilage were analysed. To stimulate ...
Frontiers6 天
Electrospun polycaprolactone/silk fibroin nanofiber scaffold with aligned fiber orientation ...
In vitro studies were conducted to investigate performance of the scaffolds on articular chondrocyte proliferation, gene expression and glycosaminoglycan secretion. Cytoskeleton staining was used to ...
Frontiers6 天
Complement system part I – molecular mechanisms of activation and regulation
Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in ...
jmg.bmj6 天
Genetic complexity of diagnostically unresolved Ehlers-Danlos syndrome
Background The Ehlers-Danlos syndromes (EDS) are heritable disorders of connective tissue (HDCT), reclassified in the 2017 nosology into 13 subtypes. The genetic basis for hypermobile Ehlers-Danlos ...
BMJ5 天
Pathophysiology of meningococcal meningitis and septicaemia
Correspondence to: Prof. M Levin, Department of Paediatrics, Faculty of Medicine, Imperial College of Science, Technology & Medicine, Norfolk Place, London W2 1PG, UK; m.levin{at}ic.ac.uk Neisseria ...