For years, scientists studying brain aging have focused on proteins and DNA. But what if a crucial piece of the puzzlehas ...

In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating—called the glycocalyx—on cells that form the blood-brain barrier, a structure that protects the brain by ...

Beijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials, Animal Experimental Centre, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union ...

内皮糖萼失调会导致血脑屏障功能障碍，这与老年性痴呆的发生和发展密切相关。当内皮糖萼受损时， 血脑屏障的通透性 增加，血液中的有害物质更容易进入大脑，从而引发一系列 神经炎症 反应，导致大脑功能逐渐衰退。

In a study with aging mice, Shi discovered significant changes in the sugary coating (glycocalyx) on cells that form the blood-brain barrier. This barrier protects the brain by filtering harmful ...

The following is a summary of “Net albumin leakage in patients in the ICU with suspected sepsis. A prospective analysis using ...

If you have diabetes, taking care of your kidneys is important. Here are some simple ways to protect them: Control your blood ...

Proteoglycans also comprise a major component of the cellular glycocalyx to influence transmembrane receptor structure/function and mechanosignaling. Through their ability to initiate biochemical and ...

Bottlebrush Barrier. The glycocalyx layer (purple, left) that coats brain blood vessels consists of numerous glycoproteins, glycolipids, and proteoglycans (right), including the bottlebrush-shaped ...