A large-scale study has revealed the impact of germline variants on proteins in 10 cancer types. Scientists from the National ...

Researchers at Mayo Clinic's Center for Individualized Medicine have discovered a rare genetic variant that can directly ...

HealthDay News — A biomarker consisting primarily of microRNA-based germline biomarkers (mirSNPs), PROSTOX, is valid for predicting radiotherapy (RT)-induced genitourinary (GU) toxicity in patients ...

Germline development is the development of the cell lineage that gives rise to the reproductive cells, called gametes, of sexually reproducing organisms. Primordial germ cells, the founder cells ...

In this review, we seek to present a comprehensive summary of the frequency of germline genetic variants in hereditary cancer syndromes in patients from LAC. The data highlight relevant differences in ...

A landmark study has revealed how inherited genetic variants, known as germline variants, play a critical role in the ...

Nurse practitioners should listen to patients’ concerns and be ready with questions when it comes to germline testing, according to an expert. Oncology nurse practitioners should be on the lookout for ...

Inherited genes, present in all cells at birth, could well be the key to understanding cancer behavior. A recent study shows ...

For example, the PEAB helped develop a plain language explanation of variants of unknown significance (VUSs) and recommended clarifying the implications of having no identified somatic or germline ...

In the realm of oncology, genetic mutations are well-established as pivotal factors predisposing individuals to various cancers. Particularly, germline ...