Recent cryo-electron microscopy (cryo-EM) and tomography data, also combined with crosslinking-mass spectrometry experiments, have uncovered detailed structural features of the coupling between a ...

Large macromolecules and subcellular structures have proven particularly good targets for imaging with cryo-EM. Some of the most exciting advances in the field have been in determining the 3D ...

Cryo-EM analysis of membrane-bound BAR protein endophilin ... the authors show that the Reh1 is positioned in the polypeptide exit tunnel of 80S ribosomes, suggesting that the growing polypeptide ...

Here, the authors show that the Reh1 is positioned in the polypeptide exit tunnel of 80S ribosomes, suggesting that the growing polypeptide chain displaces Reh1 during first round of translation.

During translation, ribosomes can pause on the nucleic acid. Researchers showed that collisions from incoming proteins get them moving again. Shelby is an assistant editor for The Scientist. She ...

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...

PLEASE NOTE: The candidate gives a layman's talk prior to the defence of the dissertation; therefore, the livestream will start fifteen minutes earlier. Cells are filled with tiny molecular machines ...

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Mitochondria are essential organelles for neuronal function and cell survival. Besides the well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid biogenesis, regulation ...