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冷球蛋白血症(cryoglobulinemia)是一种以血液中出现低温下凝固的免疫球蛋白(冷球蛋白)为特征的系统性血管炎疾病,通过免疫复合物(主要是IgG-IgM型冷球蛋白和补体)沉积血管引起白细胞碎裂性小血管炎,主要累及皮肤、肾脏、周围神经等。临床 ...
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