The moonlighting protein c-Myc is a master regulator of multiple biological processes including cell proliferation, differentiation, angiogenesis, apoptosis and metabolism. It is constitutively and ...

Besides, treatment with PD led to a significant cell cycle arrest, thereby causing subsequent apoptosis. Regarding the cell growth inhibition mechanism, PD can downregulate the protein level of c-Myc ...

The C-MYC and CD138 IHC double stain was carried ... A previous report showed that induction of apoptosis in myeloma cells by bortezomib requires upregulation of NOXA via an MYC-dependent mechanism.

Figure 1: Transgene expression and phenotype. Figure 2: K14.MYC2 mice exhibit impairment in wound healing. Figure 3: K14.MYC2 primary keratinocytes exhibit a defect in migration. Figure 4: K14 ...

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The plasmids used in this study, including pT3-EF1α-c-Met (human c-MET), pT3-EF1α-ΔN90-β-catenin (with N terminal Myc tag), pT3EF1α-c-Myc ... As cabozantinib induces HCC cell apoptosis, it is possible ...

成都医学院基础医学院解剖学与组织学胚胎学系的研究人员 Min Liu 等人在《Cell Death and Disease》期刊上发表了题为 “Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage” ...

Let's start with the quote from GNOME developer site. The single most important rule when writing code is this: check the surrounding code and try to imitate it. As a maintainer it is dismaying to ...

M. Conacci-Sorrell et al., “Myc-nick: a cytoplasmic cleavage product of Myc that promotes α-tubulin acetylation and cell differentiation,” Cell, 142:480-93, 2010. Free F1000 Evaluation When Maralice ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...

Vascular proliferation contributes to the pathobiology of atherosclerosis and is linked to other cellular processes such as inflammation, apoptosis and matrix alterations. The contribution of ...