As transcriptional factors, nuclear receptors (NRs) function as major regulators of gene expression. In particular, dysregulation of NR activity has been shown to significantly alter metabolic ...

pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...

The high mobility group A (HMGA) family is composed of four proteins, HMGA1a, HMGA1b, HMGA1c and HMGA2, encoded by two distinct genes. HMGA1 proteins are products of the same gene, generated ...