or 320 mg valsartan daily; 200 mg AHU377 daily; or placebo. Dosages were chosen so that patients treated with the low, medium, and high doses of LCZ696, respectively, would have the same ...

For the duration of trial 1, 61.0% of patients received valsartan alone, whereas 39.0% received additional antihypertensive agents at some point during the study. In trial 2, 75.8% of patients ...