Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of both upper and lower motor neurons. Despite decades of research ... Hyperexcitability: Excitability is an ...

A combination of upper and lower motor neuron dysfunction comprises the clinical ALS phenotype. Although the ALS phenotype was first observed by Charcot over 100 years ago, the site of ALS onset and ...

Contact between a motor neuron and muscle cell is usually via a specialized synapse called a neuromuscular junction. Improved muscle function, strength and fatigue measures were observed after ...

Reflexes at the elbow, crook of the arm, wrists, and ankles may also be checked. Overactive reflexes are associated with upper motor neuron lesions, which are damaged areas of the neural pathway ...

Overactive reflexes are associated with upper motor neuron lesions, which are damaged areas of the neural pathway between the cortex and corticospinal tract. However, the condition may also be ...

The therapeutic potential of brain state-dependent rTMS in the rehabilitation of upper limb motor impairment post-stroke remains unexplored. Objective: Proof-of-concept trial to assess the efficacy of ...

Pain is an example of an important sensory neuron ... precise movements. Motor neurons carry impulses away from the central nervous system (made up of the brain and spinal cord) and control the ...

1 MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, UK 2 The Graham Watts Laboratories for Research into Motor Neuron Disease, Sobell Department of Motor Neuroscience and ...

The Fish Brothers Group will open its Omoda & Jaecoo dealership in Swindon in March. ...