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Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkyňova 118, Brno 612 00, Czech Republic ...

Alpha-blockers work by blocking catecholamines from binding to alpha receptors ... angiotensin II must bind with a receptor site. ARBs prevent that from happening. As a result, blood pressure ...

This flips the NF-κB protein vs. NF-κB binding site calculus (Figure 1D, right), and our first question becomes: how do the relatively sparse NF-κB dimers decide which of the numerous potential κB ...

3.8 Transcription factor (TF)-gene regulatory network establishment Using the JASPAR TF binding site database, we constructed a TF-gene regulatory network which included 20 nodes (4 seed genes and 16 ...

Now we consider the effect of competition on the expression of SIM target genes. We measure our system with O1 as the regulatory binding site for both TF and target genes. In Figure 2A, the expression ...

Aside describes related findings that are interesting but somewhat tangential. We begin by showing how allelic manifolds can be used to measure the in vivo strength of TF binding to a specific DNA ...

However, interestingly, we observed DNaseI HS peaks, histone methylation marks (specifically H3K4me2, which is often found near promoters) and a TF binding site (specifically DAXX, a transcription ...