The tissue is divided into two layers: the outer syncytiotrophoblast composed of large mutinucelated cells and an inner layer of mononucleated cells that migrate out and fuse to form the ...

Figure 1. Pathogenesis of preeclampsia. Preeclampsia is a syndrome with heterogeneous etiology and a spectrum of phenotypes. It may appear at varying gestational ages with different degrees of ...

Gal-13 and gal-14 are predominantly expressed by the syncytiotrophoblast at the lining of the maternal-fetal interface, and their expression is down-regulated in miscarriages. Gal-13 and gal-14 bind ...

Despite increased malaria control efforts, recent reports indicate that over 1.2 million deaths due to malaria occurred in 2010. Pregnant women represent a particularly vulnerable risk group as ...

Here, we argue that the classic definitions of preeclampsia, based on concepts that are now more than 50 years old, have become outdated and that the definition could be modernized to take account of ...

Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University (L. Liu, Q.G., Y.C., S.C., L ...

It is released by special cells called syncytiotrophoblast around ten days post-conception until the placenta is fully formed later in the first trimester, which then takes over this function fully.