1Department of Urology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Search for other works by this author on: 1Department of Urology, First Affiliated Hospital, Sun Yat-sen ...

Interleukin 2 (IL-2) is the only systemic treatment currently available that is capable of curing patients with metastatic renal cell cancer (RCC). The first indications that IL-2 could mediate ...

近日，湘雅医院皮肤病医院（皮肤科）陈翔教授、刘洪教授等联合在《Nature Genetics》（自然遗传，因子指数31.7）杂志发表了 Alterations in PD-L1 succinylation shape anti-tumor ...

Oncology nurses play essential roles in the emerging field of cardio-oncology, which aims to protect patients’ heart function ...

▎药明康德内容团队编辑（来源：中南大学）恶性黑色素瘤是一种以黑色素细胞异常增殖及代谢-免疫失稳态为重要特征的致死性皮肤疾病。尽管免疫检查点抑制剂PD-1/PD-L1单抗显著改善了部分黑色素瘤患者的生存，但其反应率仍不理想，仅有15-25%的跨多种肿瘤 ...

Reversible posterior leukoencephalopathy syndrome is characterized clinically by headache, abnormalities of mental status and visual perception, and seizures. Despite its diverse causes, common ...

The mean absorbed radiation dose to tumors was 8.9 Gy/GBq, compared with 0.27 Gy/GBq in the kidneys and 0.13 Gy/GBq in the salivary glands.

It was approved by the MHRA on the back of the CheckMate-9ER trial, which compared the combination with Pfizer’s Sutent (sunitinib) in 651 patients with advanced RCC and found that it reduced ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...