ATLANTA — The US Institute of Medicine (IOM) is looking into whether polio vaccines contaminated with the simian virus SV40 — thought to inactivate p53 and Rb — and given 40 years ago have caused a ...

"The variants of spike proteins can be divided into five distinct clusters based on the similarity of their amino acid sequences and functions," revealed Associate Professor Md. Altaf-Ul-Amin.

p53 and RB are at the heart of the two main tumour-suppressor pathways that control cellular responses to potentially oncogenic stimuli. Each pathway consists of several upstream regulators and ...