Objective: Nano-sized drug delivery systems (NSDDSs) offer a promising therapeutic technology with sufficient biocompatibility, stability, and drug-loading rates towards efficient drug delivery to ...

In the last decade, immune checkpoint blockade (ICB) has revolutionized the standard of treatment for solid tumors. Despite success in several immunogenic ... and the possibility that other mechanisms ...

Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors and were among the first solid tumor types for which such a novel treatment (in this case imatinib) became available. The ...

This will help advance the field of organoid-based cancer models." The review on tissue dissociation techniques is poised to make a significant impact on oncology research, especially for solid ...

Runimotamab is under clinical development by Genentech USA and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 69% phase transition success rate ...

However, CAR-T cell application in solid tumors remains challenging. There is an unmet clinical need for better cellular therapies for solid tumors. The team of researchers, led by Xiaowei ...

Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. BGB-43395 is under development for the treatment of non-small cell ...

For the retrospective study, an ensemble 3D U-Net deep learning model was trained for lung tumor detection and segmentation using 1,504 CT scans with 1,828 segmented lung tumors. The model was ...

Learn about our Editorial Policies. Chimeric antigen receptor (CAR) T cell therapy leverages patients’ immune systems to fight cancer. This immunotherapy greatly expanded treatment options for cancers ...

AI Innovation Unlocks Non-Surgical Way to Detect Brain Cancer Spread Jan. 14, 2025 — Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain ...