The past decade has seen significant advances in our understanding of skeletal homeostasis and the mechanisms that mediate the loss of bone integrity in disease. Recent breakthroughs have arisen ...

Spinal cord injury leads to loss of innervation of skeletal muscle, decreased motor function ... NF-κB activates ubiquitin-proteasome System (UPS) and degrades proteins by binding E1, E2, and E3, with ...

The musculoskeletal system is an organ system comprising the ... secreted factors and other biochemical stimuli to maintain homeostasis, growth and function. This Review discusses key factors ...

Discover how hydration plays a vital role in diabetes management by improving blood sugar control and boosting insulin ...

2). While the energy homeostasis system can therefore respond to a change of adiposity in either direction, this analysis provides a mechanistic and testable explanation for its apparent bias ...

Mar. 4, 2025 — A research team has uncovered the neural mechanisms underlying the processing of pain and itch in the anterior cingulate cortex (ACC). This study provides new insights into how ...

An international study led by the University of Granada (UGR) has revealed that melatonin, known for its ability to regulate ...

Learning how to design scalable systems will help you become a better engineer. System design is a broad topic. There is a vast amount of resources scattered throughout the web on system design ...

Stable isotope amino acid tracers have been pivotal in understanding muscle protein synthesis and breakdown, helping reveal ...

Feb. 25, 2025 — On Wednesday 26 February, a thermal imaging camera blasted off to the Moon as part of NASA's Lunar Trailblazer mission. This aims to map sources of water on the Moon to shed ...

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