Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.

Camber is introducing sirolimus oral solution. The medication is an mTOR inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in patients aged greater or equal to 13 years ...

3 mL blood in a LAVENDER top tube (EDTA); redraw if specimen clotted. Specimen is stable for up to 7 days refrigerated (2 to 8 C). If testing is delayed more than 7 days, store frozen at -10 C or less ...

Sirolimus was shown to have less neurotoxicity in the canine cerebral vasculature. The feasibility and safety of a sirolimus coated balloon (SCB) for ICAS have never been evaluated in humans. We ...

The SirPAD (Major adverse limb events in patients with femoro-popliteal and below-the-knee peripheral arterial disease treated with either sirolimus-coated or uncoated balloon) randomised controlled ...