Sickle cell conditions are genetic blood disorders that affect haemoglobin, the molecule in red blood cells responsible for ...

Scientists have been looking for ways to increase fetal hemoglobin in more people with sickle cell disease, says Ambroise Wonkam, M.D., Ph.D., the Henry J. Knott Director of the McKusick-Nathans ...

Bluebird Bio and Xcellbio have entered into an agreement to support the commercialization of sickle cell gene therapy ...

Knott Director of the McKusick-Nathans Institute and Professor in Medical Genetics in the Department ... with permission from 3,751 people with sickle cell disease. Fetal hemoglobin shuttles ...

Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

A marker linked to inflammation, C-reactive protein, may increase significantly during the follicular phase of the menstrual cycle in female patients with sickle cell disease (SCD), according to ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

Sickle cell anaemia is a genetic blood disorder characterised by the production of an abnormal haemoglobin, known as haemoglobin S. Sickle cell disease changes the shape of blood cells into a ...

At Fred Hutch Cancer Center, we care for adults with sickle cell disease. Along with our local patients, we see many people from farther away, like Alaska. They get most of their care near home, but ...

For the first time, two U.S. teenagers with sickle cell disease will be able to go swimming on their spring break, thanks to SCD treatments.

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ... Brains of People With ...