Utilizing single cell RNA-sequencing and flow cytometry, we discerned STAT1-regulated genes in TI-associated resident and recruited splenic myeloid populations. The temporal dynamics of TI were ...

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug ...

Utilizing single cell RNA-sequencing and flow cytometry, we discerned STAT1-regulated genes in TI-associated resident and recruited splenic myeloid populations. The temporal dynamics of TI were ...

促进 STAT1 在丝氨酸 727位点（Ser727）的磷酸化，并增强 ISG15 的表达和分泌。 这种在癌细胞中的信号级联反应能动员自然杀伤（NK）细胞，增强其细胞 ...

Hepatocellular carcinoma (HCC) mostly occurs in the background of liver fibrosis, and activated hepatic stellate cells (HSCs) exist in HCC tissues and adjacent tissues. HSC activation is involved ...

Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a ...

Jens H Nielsen, University of Copenhagen, Department of Biomedical Research, Panum Institute, Bldg 6.5, Blegdamsvej 3C, DK-2200 Copenhagen N, Denmark Disclosure: The authors have no other relevant ...