Together, these snRNAs and proteins form small nuclear ribonucleoprotein particles (snRNPs), setting the stage for splicing. 1 The traditional view posits that spliceosome formation is a stepwise ...

Splicing is a basic requirement for producing proteins that fulfill an organism's vital functions. Researchers have succeeded for the first time in depicting a faultily 'blocked' spliceosome at ...

Splicing is a basic requirement for producing proteins that fulfill an organism's vital functions. Faulty functioning of a spliceosome can lead to a variety of serious diseases. The genetic ...

The outcome varies depending on which parts are cut out, resulting in distinct blueprints for different proteins. This process is crucial for the life of the cell. "The spliceosome is composed of ...