为了揭开这个谜团，他们进行了深入研究，并将研究成果发表在《Molecular Medicine》期刊上，论文题目是 “Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR - 495/SKP2/Runx2 axis”。

Federal University of São Carlos, Graduate Program in Materials Science and Engineering, Rod. Washington Luís, km 235─Monjolinho, São Carlos, SP 13565-905, Brazil Federal University of São Carlos, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Functionally graded scaffolds (FGSs) designed for bone tissue regeneration exhibit ...

A stress fracture is generally the result of overuse or repeated trauma to a bone. Also known as "fatigue fractures," stress fractures may occur when muscles become fatigued or overloaded and transfer ...

They typically occur as a result of a fall from a height, such as from a ladder. Other causes of a calcaneus fracture include automobile crashes and sports injuries. The calcaneus can also sustain a ...

Objectives Interleukin (IL)-17 signalling has been shown to be a key regulator of disease in ankylosing spondylitis (AS) with several IL-17 blockers currently clinically approved. Despite this, the ...

While fracture healing occurs in most cases without delay ... 1:100), Osx (rabbit polyclonal, sc-22536-R, 1:200), Runx2 (EPR14334 conjugated AF647, ab215955, 1:100), Sox9 (EPR14335 unconjugated, ...

A concussion is an injury to the head area that may cause instant loss of awareness or alertness for a few minutes up to a few hours after the traumatic event. Skull fracture. A skull fracture is a ...

The primary antibodies included Runx2 (1:100, #12556, Cell Signaling Technology ... p < 0.05 was considered statistically significant. Condyle development and fracture repair represents an important ...

Runx2 is expressed in the perimysial populations and CNC-derived progenitor cells during soft palate development To elucidate the dynamic process by which CNC-derived cells differentiate during soft ...