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肝星状细胞分化的轨迹分析揭示了细胞承诺和纤维化的代谢调节
在这里,作者研究了人类多能干细胞向肝星状细胞(dihsc)分化的蛋白质组轨迹,并确定RORA是控制代谢重编程的关键转录因子,对dihsc的承诺、身份和静态表型至关重要。 肝星状细胞分化轨迹分析揭示细胞命运与纤维化的代谢调控机制 来自 Institut d’Investigacions ...
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